LH-RH, salmon

CAS No. 86073-88-3

LH-RH, salmon( Luteinizing Hormone Releasing Hormone (LH-RH), salmon )

Catalog No. M29811 CAS No. 86073-88-3

Luteinizing Hormone Releasing Hormone (LH-RH) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive function.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    LH-RH, salmon
  • Note
    Research use only, not for human use.
  • Brief Description
    Luteinizing Hormone Releasing Hormone (LH-RH) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive function.
  • Description
    Luteinizing Hormone Releasing Hormone (LH-RH) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive function.(In Vitro):Luteinizing hormone-releasing hormone (LHRH) is the key hormone in the control of reproductive functions.LHRH acts as an antimitogenic factor through the activation of the Gi-cAMP intracellular signaling pathway. LHRH might act as an inhibitory factor on both cell proliferation and metastatic behavior in melanoma cells. The hypothalamic decapeptide luteinizing hormone-releasing hormone (LHRH) plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn promote gonadal functions and regulate sex steroid secretion. The effects of LHRH are mediated by high-affinity G protein-coupled LHRH-receptor (LHRH-R) on pituitary gonadotropes. The responses to LHRH vary under different conditions and critically depend on the regimens of administration and doses delivered to gonadotrope cells.
  • In Vitro
    Luteinizing hormone-releasing hormone (LHRH) is the key hormone in the control of reproductive functions.LHRH acts as an antimitogenic factor through the activation of the Gi-cAMP intracellular signaling pathway. LHRH might act as an inhibitory factor on both cell proliferation and metastatic behavior in melanoma cells. The hypothalamic decapeptide luteinizing hormone-releasing hormone (LHRH) plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn promote gonadal functions and regulate sex steroid secretion. The effects of LHRH are mediated by high-affinity G protein-coupled LHRH-receptor (LHRH-R) on pituitary gonadotropes. The responses to LHRH vary under different conditions and critically depend on the regimens of administration and doses delivered to gonadotrope cells.
  • In Vivo
    ——
  • Synonyms
    Luteinizing Hormone Releasing Hormone (LH-RH), salmon
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    86073-88-3
  • Formula Weight
    1212.31
  • Molecular Formula
    C60H73N15O13
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Sequence:{Glp}-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-NH2

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Moretti RM, et al. Inhibitory activity of luteinizing hormone-releasing hormone on tumor growth and progression. Endocr Relat Cancer. 2003 Jun;10(2):161-7.
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